Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor

Yuhui Huang, Mami Sumida, Motofumi Kumazoe, Kaori Sugihara, Yumi Suemasu, Shuhei Yamada, Shuya Yamashita, Jyunichi Miyakawa, Takashi Takahashi, Hiroshi Tanaka, Yoshinori Fujimura, Hirofumi Tachibana

Chemical Communications · 2017

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Summary

Green tea polyphenol (-)-epigallocatechin-3-O-gallate (EGCG) has been attributed to the activation of its cell surface sensing receptor 67 kDa laminin receptor (67LR). However, the action of EGCG to activate 67LR remains unknown. Here we show that EGCG undergoes oligomer formation on its surface receptor 67LR.

Source type
Peer-reviewed study
DOI
10.1039/c6cc09504f
Catalogue ID
BFmoakvgtk-nvnkis
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