Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells

Motoshi Suzuki, Ke Cao, Seiichi Kato, Yuji Komizu, Naoki Mizutani, Kouji Tanaka, Chinatsu Arima, Mei-Chee Tai, Kiyoshi Yanagisawa, Norie Togawa, Takahiro Shiraishi, Noriyasu Usami, Tetsuo Taniguchi, Takayuki Fukui, Kohei Yokoi, Keiko Wakahara, Yoshinori Hasegawa, Yukiko Mizutani, Yasuyuki Igarashi, Jin‐ichi Inokuchi, Soichiro Iwaki, Satoshi Fujii, Akira Satou, Yōko Matsumoto, Ryuichi Ueoka, Keiko Tamiya‐Koizumi, Takashi Murate, Mitsuhiro Nakamura, Mamoru Kyogashima, Takashi Takahashi

Journal of Clinical Investigation · 2019

Read source ↗ All evidence

Summary

The corresponding author recently notified the JCI that the patient data presented in Figure Analysis of the correct patient data set does not show a significant difference in CERS6 expression in human lung adenocarcinomas with positive invasive growth (definite) compared with those with negligible invasive growth or without invasive growth (focal/none). The Editors have requested an institutional investigation into this matter, and we will inform our readers of the outcome when the investigation is complete.

Source type
Peer-reviewed study
DOI
10.1172/jci131245
Catalogue ID
BFmoakvgtk-qqkvv6
Pulse AI · ask about this record

Dig deeper with Pulse AI.

Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.