Summary
We have been developing a medical imaging technique using a Compton camera. This study evaluates the feasibility of clear imaging with <sup>99m</sup>Tc and <sup>18</sup>F simultaneously, and demonstrates in vivo imaging with <sup>99m</sup>Tc and/or <sup>18</sup>F. We used a Compton camera with silicon and cadmium telluride (Si/CdTe) semiconductors. We estimated the imaging performance of the Compton camera for 141 keV and 511 keV gamma rays from <sup>99m</sup>Tc and <sup>22</sup>Na, respectively. Next, we simultaneously imaged <sup>99m</sup>Tc and <sup>18</sup>F point sources to evaluate the cross-talk artifacts produced by a higher energy gamma-ray background. Then, in the in vivo experiments, three rats were injected with <sup>99m</sup>Tc-dimercaptosuccinic acid and/or <sup>18</sup>F-flu
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