Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition

Liesl Wandrag, Mario Siervo, Heather L. Riley, Maryam Khosravi, Bernadette Fernandez, Carl A. Leckstrom, Daniel Martín, Kay Mitchell, Denny Levett, Hugh Montgomery, Monty Mythen, M Stroud, Michael P. W. Grocott, Martin Feelisch

Redox Biology · 2017

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Summary

The putative role of GLP-1 and nitrite as mediators of the effects of hypoxia on FFM is an intriguing finding. If confirmed, nutritional and pharmacological interventions targeting these pathways may offer new avenues for prevention and treatment of sarcopenia.

Source type
Peer-reviewed study
DOI
10.1016/j.redox.2017.05.004
Catalogue ID
BFmoakvpzf-a92z8p
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