Pulse Brain · Growing Health Evidence Index
Peer-reviewed

High-altitude population neonatal and maternal phenotypes associated with birthweight protection

Padma Dolma, P. T. Angchuk, Vandana Jain, Vatsla Dadhwal, Dalvir Kular, David Williams, Hugh Montgomery, Sara Hillman

Pediatric Research · 2021

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Summary

Reduced foetal oxygen delivery seen in native lowlanders who gestate at HA causes foetal growth restriction-an effect thought to be mitigated in native HA populations. We found that greater maternal body mass and UtA diameter were associated with increased offspring birthweight in a (Ladakh) HA population. This supports a role for them as physiological mediators of adaptation and provides insights into potential mechanisms that may treat hypoxia-related growth issues.

Source type
Peer-reviewed study
DOI
10.1038/s41390-021-01593-5
Catalogue ID
BFmoakvpzf-gcdgmz
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