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Peer-reviewed

Manganese Nanoparticles in Diagnostics and in Identifying the Antitumor Activity of Viper Venom in Experiment

Topchiyeva Sh.A., Yildiz L.Z., Jefferson Rocha de A, Anar Gojayev, Khaironizam M.Z, Mehrabova M.M

Research Journal of Pharmacology and Pharmacodynamics · 2025

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Summary

The purpose of the work is to study the effect of a mixture of venom proteins and manganese nanoparticles on the composition of blood cells. Materials and methods. Experiments were carried out on 20 white outbred laboratory rats, weighing in the range of 200-220g, which were intraperitoneally injected with viper poison (Macrovipera lebetina obtusa) at a dose of 0.02mg/kg body weight and manganese nanoparticles. Research results and discussion. As a result, after the introduction of viper venom in combination with manganese nanoparticles, significant changes were observed in the blood of experimental animals. The content of leukocytes in the blood decreased by 12.1%, 19.5%, 26%, granulocytes, monocytes and neutrophils increased, respectively, by 8.6%, 3.8%, 3.9%. Analysis of daily blood sho

Source type
Peer-reviewed study
DOI
10.52711/2321-5836.2025.00003
Catalogue ID
BFmoakvqks-2dgt17
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