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Peer-reviewed

Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration

Veronika Skrivankova, Rebecca C. Richmond, Benjamin Woolf, Neil M Davies, Sonja A. Swanson, Tyler J. VanderWeele, Nicholas J. Timpson, Julian P. T. Higgins, Niki Dimou, Claudia Langenberg, Elizabeth Loder, Robert Golub, Matthias Egger, George Davey Smith, J. Brent Richards

BMJ · 2021

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Summary

In observational epidemiology, mendelian randomisation (MR) studies provide an opportunity to study the causal association between an exposure and an outcome while reducing the risk of certain biases Little consensus exists around the reporting of MR studies, and the quality of reporting of these studies has been inconsistent; many MR study reports do not state or examine the various assumptions of MR and report insufficient details on the data sources STROBE-MR (strengthening the reporting of observational studies in epidemiology using mendelian randomisation), a checklist of 20 reporting items, has been developed for the communication of MR studies This article explains the rationale of these checklist items and provides examples of transparent reporting MR study authors, reviewers, and

Source type
Peer-reviewed study
DOI
10.1136/bmj.n2233
Catalogue ID
BFmoef2ocf-a2kgsm
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