Caroline Dale, Ghazaleh Fatemifar, Tom Palmer, Jon White, David Prieto‐Merino, Delilah Zabaneh, Jorgen Engmann, Tina Shah, Andrew Wong, Helen R. Warren, Stela McLachlan, Stella Trompet, Max Moldovan, Richard Morris, Reecha Sofat, Meena Kumari, Elina Hyppönen, Barbara J. Jefferis, Tom R. Gaunt, Yoav Ben‐Shlomo, Ang Zhou, Aleksandra Gentry‐Maharaj, Andy Ryan, Renée de Mutsert, Raymond Noordam, Mark J. Caulfield, J. Wouter Jukema, Bradford B. Worrall, Patricia B. Munroe, Usha Menon, Chris Power, Diana Kuh, Debbie A. Lawlor, Steve E. Humphries, Dennis O. Mook‐Kanamori, Naveed Sattar, Mika Kivimäki, Jacqueline F. Price, George Davey Smith, Frank Dudbridge, Aroon D. Hingorani, Michael V. Holmes, Juan P. Casas

doi:10.1161/circulationaha.116.026560

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus

Caroline Dale, Ghazaleh Fatemifar, Tom Palmer, Jon White, David Prieto‐Merino, Delilah Zabaneh, Jorgen Engmann, Tina Shah, Andrew Wong, Helen R. Warren, Stela McLachlan, Stella Trompet, Max Moldovan, Richard Morris, Reecha Sofat, Meena Kumari, Elina Hyppönen, Barbara J. Jefferis, Tom R. Gaunt, Yoav Ben‐Shlomo, Ang Zhou, Aleksandra Gentry‐Maharaj, Andy Ryan, Renée de Mutsert, Raymond Noordam, Mark J. Caulfield, J. Wouter Jukema, Bradford B. Worrall, Patricia B. Munroe, Usha Menon, Chris Power, Diana Kuh, Debbie A. Lawlor, Steve E. Humphries, Dennis O. Mook‐Kanamori, Naveed Sattar, Mika Kivimäki, Jacqueline F. Price, George Davey Smith, Frank Dudbridge, Aroon D. Hingorani, Michael V. Holmes, Juan P. Casas

Circulation · 2017

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Summary

Both general and central adiposity have causal effects on CHD and type 2 diabetes mellitus. Central adiposity may have a stronger effect on stroke risk. Future estimates of the burden of adiposity on health should include measures of central and general adiposity.

Source type: Peer-reviewed study
DOI: 10.1161/circulationaha.116.026560
Catalogue ID: BFmoef2ocf-lfsng1

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