Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Re-defining pT4b buccal mucosa squamous cell carcinoma: Looking beyond palliation in select patients

Prateek Jain, Kapila Manikantan, Gary M. Clark, Indranil Mallick, Sanjoy Chatterjee, Indu Arun, Paromita Roy, Lateef Zameer, Pattatheyil Arun

Oral Oncology Reports · 2024

Read source ↗ All evidence

Summary

Reports in the last 2 decades suggest that selected patients with masticator space invasion can be treated surgically with reasonable survival. This study is an attempt to identify prognosticators for disease free (DFS) and overall survival (OS) in surgically treated pT4 buccal mucosa squamous cell carcinoma (BMSCC) patients. The cohort for this retrospective study comprised 213 patients with pT4a/b BMSCC, treated with curative intent surgery from August 2011 through December 2019. Depending upon masticator space invasion (MSI) patients were divided into 3 groups viz. pT4a, involvement of masseter and/or medial pterygoid (Low MSI) and involvement of lateral pterygoid and/or temporalis (High MSI). The median follow-up in this study was 45 (2–123) months. The 5-year DFS was 53 %, 42 % and 21

Source type
Peer-reviewed study
DOI
10.1016/j.oor.2024.100616
Catalogue ID
BFmoicpf59-t3l5ky
Pulse AI · ask about this record

Dig deeper with Pulse AI.

Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.