Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Caudwell Xtreme Everest: A prospective study of the effects of environmental hypoxia on cognitive functioning

Konstadina Griva, Jan Stygall, Mark H. Wilson, Daniel Martín, Denny Levett, Kay Mitchell, Monty Mythen, Hugh Montgomery, Mike P. Grocott, Golnar Aref-Adib, Mark Edsell, Tracie Plant, Chris Imray, Debbie Cooke, Jane Harrington, Maryam Khosravi, Stanton Newman

PLoS ONE · 2017

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Summary

BACKGROUND: The neuropsychological consequences of exposure to environmental hypobaric hypoxia (EHH) remain unclear. We thus investigated them in a large group of healthy volunteers who trekked to Mount Everest base camp (5,300 m). METHODS: A neuropsychological (NP) test battery assessing memory, language, attention, and executive function was administered to 198 participants (age 44.5±13.7 years; 60% male). These were studied at baseline (sea level), 3,500 m (Namche Bazaar), 5,300 m (Everest Base Camp) and on return to 1,300 m (Kathmandu) (attrition rate 23.7%). A comparable control group (n = 25; age 44.5±14.1 years; 60% male) for comparison with trekkers was tested at/or near sea level over an equivalent timeframe so as to account for learning effects associated with repeat testing. The

Source type
Peer-reviewed study
DOI
10.1371/journal.pone.0174277
Catalogue ID
BFmokjo2bz-bxsh7k
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