Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

When assessing representative images of fine‐needle aspirate cytological smears of canine mast cell tumours, interobserver agreement is influenced by educational attainment

Shana De Vos, Bart J. G. Broeckx, Francesco Cian, M. van der Ploeg, H. De Cock, Ward De Spiegelaere, H. de Rooster

Journal of Small Animal Practice · 2025

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Summary

This study investigated how observer educational attainment influences diagnostic consistency in veterinary cytopathology, specifically for canine mast cell tumours. Twenty-five observers stratified by qualification level (from board-certified specialists to veterinary students) interpreted 36 sets of cytological images without additional training. The findings demonstrate that board-certified internal medicine specialists achieved significantly higher interobserver agreement than less-experienced observers, with statistically significant differences in mast cell tumour diagnosis and mast cell identification, suggesting that formal training and experience substantially improve diagnostic consistency in this presumptively straightforward diagnostic task.

Regional applicability

These findings are directly applicable to UK veterinary practice and training. The results support the case for standardised cytopathology training and specialist referral protocols within UK small animal veterinary medicine, and may inform continuing professional development requirements for practitioners performing cytological diagnostics.

Key measures

Interobserver agreement, kappa coefficient, diagnostic accuracy for mast cell tumour presence, mast cell presence, eosinophils, and lymphocytes across five observer groups

Outcomes reported

The study measured interobserver agreement and kappa statistics across five groups of observers with differing educational attainment (from board-certified specialists to final-year veterinary students) when interpreting cytological smears of canine mast cell tumours versus non-mast cell tumours.

Theme
General food systems / other
Subject
Out of scope / non-food
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
Europe
System type
Human clinical
DOI
10.1111/jsap.13883
Catalogue ID
BFmokjo3rj-ulp5j9

Topic tags

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