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Tier 3 — Observational / field trialPeer-reviewed

QUALITY CONTROL STANDARDIZATION OF AQUEOUS AND ETHANOL EXTRACTS OF CRATEVA ADANSONII DC. STEM BARK

Nyambura Achieng M., Jefferson Rocha de A

International journal of applied ayurved research. · 2025

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Summary

This laboratory study established quality control standardisation parameters for stem bark extracts of Crateva adansonii (Varuna), a traditional medicinal plant indicated for urinary calculi in Ayurvedic practice. Physical and chemical analyses demonstrated that most parameters fell within acceptable limits, with water-soluble extracts yielding higher extractive values than ethanol extracts. Phytochemical profiling identified alkaloids, tannins, flavonoids, steroids, glycosides and proteins in both extracts, alongside extract-specific constituents (saponins in aqueous, terpenoids in ethanol), providing a basis for quality assurance of herbal preparations.

UK applicability

This work has limited direct applicability to UK farming or policy contexts, as it concerns laboratory standardisation of a tropical medicinal plant species not widely cultivated in the United Kingdom. However, the methodological approach to herbal product quality standardisation may inform UK regulatory frameworks for botanical supplements and traditional medicine registration.

Key measures

Foreign matter content, total ash, acid-insoluble ash, water-soluble ash, loss on drying, water-soluble and alcohol-soluble extractive values, swelling index, foaming index, phytochemical screening (alkaloids, tannins, flavonoids, steroids, glycosides, proteins, saponins, terpenoids, carbohydrates), thin-layer chromatography Rf values

Outcomes reported

The study determined standardization parameters for Crateva adansonii stem bark through organoleptic, physical, chemical and biological analyses. Physical parameters, phytochemical composition and thin-layer chromatography profiles were characterised for both aqueous and ethanol extracts.

Theme
Measurement & metrics
Subject
Phytochemicals & bioactive compounds
Study type
Research
Study design
Laboratory analytical study
Source type
Peer-reviewed study
Status
Published
System type
Laboratory / in vitro
DOI
10.70057/ijaar.2024.61101
Catalogue ID
BFmor3g4qi-ehszm1

Topic tags

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