Pulse Brain · Growing Health Evidence Index
Tier 2 — RCT / large cohortPeer-reviewed

Hybrid Coronary Revascularization for the Treatment of Multivessel Coronary Artery Disease

John D. Puskas, Michael E. Halkos, Joseph J. DeRose, Emilia Bagiella, Marissa A. Miller, Jessica Overbey, Johannes Bonatti, V.S. Srinivas, Mark R. Vesely, Francis P. Sutter, Janine Lynch, Katherine Kirkwood, Timothy Shapiro, Konstantinos Dean Boudoulas, Juan A. Crestanello, Thomas Gehrig, Peter K. Smith, Michael Ragosta, Steven J. Hoff, David Zhao, Annetine C. Gelijns, Wilson Y. Szeto, Giora Weisz, Michael Argenziano, Thomas A. Vassiliades, Henry Liberman, William Matthai, Deborah D. Ascheim

Journal of the American College of Cardiology · 2016

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Summary

This randomised controlled trial, published in the Journal of the American College of Cardiology, examined hybrid coronary revascularisation as a treatment approach for multivessel coronary artery disease. Hybrid revascularisation combines minimally invasive direct coronary artery bypass with percutaneous coronary intervention to potentially optimise outcomes. The study assessed safety, efficacy, and clinical outcomes in a multicentre US setting.

UK applicability

Findings are directly applicable to UK cardiology practice, as this represents an advanced intervention approach potentially relevant to NHS cardiac centres. However, implementation would depend on local infrastructure, training capacity, and commissioning decisions within UK cardiac networks.

Key measures

Major adverse cardiac and cerebrovascular events (MACCE), mortality, myocardial infarction, revascularisation rates, and functional outcomes

Outcomes reported

The study evaluated the safety and efficacy of hybrid coronary revascularisation (combining minimally invasive direct coronary artery bypass with percutaneous coronary intervention) compared to conventional approaches for treating multivessel coronary artery disease.

Theme
Nutrition & health
Subject
Dietary patterns & chronic disease
Study type
Research
Study design
RCT
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1016/j.jacc.2016.05.032
Catalogue ID
BFmor3gavc-w354k9

Topic tags

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