Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Progression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation

Philippe B. Bertrand, Jessica Overbey, Xin Zeng, Robert A. Levine, Gorav Ailawadi, Michael A. Acker, Peter K. Smith, Vinod H. Thourani, Emilia Bagiella, Marissa A. Miller, Lopa Gupta, Michael J. Mack, A. Marc Gillinov, Gennaro Giustino, Alan J. Moskowitz, Annetine C. Gelijns, Michael E. Bowdish, Patrick T. O’Gara, James S. Gammie, Judy Hung, Marissa A. Miller, Wendy C. Taddei-Peters, Dennis Buxton, Ron Caulder, Nancy L. Geller, David Gordon, Neal O. Jeffries, Albert Lee, Claudia S. Moy, Ilana Kogan Gombos, Jennifer Ralph, Richard D. Weisel, Timothy J. Gardner, Patrick T. O’Gara, Eric A. Rose, Annetine C. Gelijns, Michael K. Parides, Deborah D. Ascheim, Alan J. Moskowitz, Emilia Bagiella, Ellen Moquete, Helena Chang, Melissa Chase, James Foo, Yingchun Chen, Seth Goldfarb, Lopa Gupta, Katherine Kirkwood, Edlira Dobrev, Ron Levitan, Karen O’Sullivan, Jessica Overbey, Milerva Santos, Deborah Williams, Michael Weglinski, Paula Williams, Carrie Wood, Xia Ye, Sten Lyager Nielsen, Henrik Wiggers, Henning Malgaard, Michael Mack, Tracine Adame, Natalie Settele, Jenny Adams, William Ryan, Robert L. Smith, Paul Grayburn, Frederick Y. Chen, Anju Nohria, Lawrence Cohn, Prem Shekar, Sary Aranki, Gregory Couper, Michael Davidson, R. Morton Bolman, Anne Burgess, Debra Conboy, Rita Lawrence, Nicolas Noiseux, Louis-Mathieu Stevens, Ignacio Prieto, Fadi Basile, Joannie Dionne, Julie Fecteau, Eugene H. Blackstone, A. Marc Gillinov, Pamela Lackner, Leoma Berroteran, Diana Dolney, Suzanne Fleming, Roberta Palumbo, Christine Whitman, Kathy Sankovic, Denise Kosty Sweeney, Carrie Geither, Kristen Doud, Gregory Pattakos, Pamela A. Clarke, Michael Argenziano

Journal of the American College of Cardiology · 2021

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Summary

This observational study from 2021, published in the Journal of the American College of Cardiology, examined the natural history and progression of tricuspid regurgitation in patients treated surgically for ischaemic mitral regurgitation. The research, involving a large multicentre cohort with extensive follow-up data, as suggested by the authorship and journal scope, sought to characterise TR severity trajectories and their association with clinical outcomes post-mitral valve surgery.

Regional applicability

This study was conducted in the United States and addresses cardiothoracic surgical practice and outcomes. Findings are transferable to United Kingdom cardiothoracic units insofar as surgical techniques and patient populations are comparable; however, local clinical outcomes may vary depending on operative experience, post-operative management protocols, and patient case-mix.

Key measures

Tricuspid regurgitation severity grade, left ventricular ejection fraction, right ventricular function, mortality, morbidity, and symptom status assessed via echocardiography and clinical follow-up

Outcomes reported

The study examined the progression of tricuspid regurgitation (TR) in patients undergoing surgical repair for ischaemic mitral regurgitation, tracking TR severity and associated clinical outcomes over time.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1016/j.jacc.2020.11.066
Catalogue ID
BFmowc2cfp-dw3iey

Topic tags

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