Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Artificial miRNAs and target-mimics as potential tools for crop improvement.

Rabuma T, Sanan-Mishra N.

Physiol Mol Biol Plants · 2025

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Summary

This narrative review examines artificial miRNAs and target-mimic constructs as emerging biotechnological approaches for targeted crop improvement. The authors likely discuss the molecular mechanisms, design considerations, and practical applications of these gene-silencing tools across crop species, whilst addressing technical challenges and regulatory considerations relevant to their deployment in agricultural systems.

UK applicability

The findings are applicable to UK crop breeding and biotech regulation, though adoption would depend on alignment with UK post-Brexit GMO policy and consumer acceptance. Current UK regulations require case-by-case assessment of gene-edited crops, which may influence the adoption timeline of these molecular tools.

Key measures

Literature synthesis on miRNA design strategies, target specificity, efficacy in trait modification, and crop species tested

Outcomes reported

The study reviews artificial miRNA and target-mimic technologies as molecular tools for modulating gene expression in crop plants. It likely synthesises evidence on how these approaches can confer agronomic traits such as stress tolerance, yield, or pest resistance.

Theme
Climate & resilience
Subject
Molecular genetics and biotechnological crop improvement
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
Global
System type
Arable cereals, Horticulture
DOI
10.1007/s12298-025-01550-0
Catalogue ID
NRmo3d4gae-07y

Topic tags

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