Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

The role of nutrition and gut microbiome in childhood brain development and behavior.

Jiang Y, Li Y.

Front Nutr · 2025

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Summary

This narrative review synthesises evidence linking nutritional status and gut microbiota composition to childhood brain development and behavioural outcomes. The authors integrate findings from clinical, observational and experimental studies to elucidate mechanistic pathways through which dietary quality influences the microbiota-gut-brain axis during critical developmental windows. The work aims to inform understanding of how early nutrition shapes neurodevelopment.

Regional applicability

The mechanistic insights on nutrition, microbiota and neurodevelopment are relevant to UK paediatric practice and public health policy. Applicability of specific dietary recommendations would depend on alignment with UK dietary guidelines and food system contexts.

Key measures

Microbiota composition, dietary quality metrics, neurodevelopmental assessments, behavioural outcomes, mechanistic pathways of the microbiota-gut-brain axis

Outcomes reported

The review synthesises evidence linking dietary nutrition and gut microbiota composition to childhood brain development and behavioural outcomes. The authors examine mechanistic pathways through which dietary quality influences the microbiota-gut-brain axis during critical developmental windows.

Theme
Nutrition & health
Subject
Maternal, infant & child nutrition
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.3389/fnut.2025.1590172
Catalogue ID
NRmo3d4gae-0c1

Topic tags

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