Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Benefits of Nutrients and Phytonutrients in Nuts and Legumes on Platelet Aggregation Through DNA Methylation

Siwaphorn Chaimati; Jintana Sirivarasai; Nareerat Sutjarit

Molecular Nutrition & Food Research · 2025

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Summary

ABSTRACT Platelets play a central role in hemostasis and thrombosis, but their hyperactivity is closely associated with an increased risk of cardiovascular diseases (CVDs). Appearing evidence emphasizes the importance of plant‐based diets, especially those rich in nuts and legumes, which are associated with modulating platelet function and reducing CVD risks. Nuts and legumes are abundant sources of nutrients, including mono/polyunsaturated fatty acids, fiber, vitamins, minerals, and bioactive compounds, such as polyphenols, flavonoids, and phenolic acids. These components, both nutrients and bioactive compounds, were reported to have antiplatelet aggregation properties. Furthermore, epigenetic mechanisms, particularly DNA methylation, regulate gene expression, including

Source type
Peer-reviewed study
DOI
10.1002/mnfr.70297
Catalogue ID
NRmo3d4gae-0dt
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