Summary
The antidiabetic property of Nelumbo nucifera rhizome, a medicinal food used to manage diabetes mellitus in Sri Lankan native medicine has not been scientifically explained yet. The Lotus rhizome is found to compose several medicinally active compounds with anti-diabetic properties, including Betulinic acid, Tryptophan, Nuciferin, isoquercetin, Rutin, β- Sitosterol, Stigmasterol, and Fibre. A narrator review was conducted to identify the scientific basis of the antidiabetic property with the explanation of the molecular level mechanisms of glucose homeostasis of these medicinally active components. This article reviews the bio-physiological mechanisms of glucose homeostasis by Tryptophan, Nuciferin, and isoquercetin A literature search was done in PubMed and Google Scholar databases using
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