Summary
This narrative review, published in the International Journal of Molecular Sciences in 2025, synthesises current progress in the application of integrative multi-omics strategies — combining genomic, transcriptomic, proteomic, metabolomic and related data layers — to unravel the biological basis of agriculturally important crop traits. The authors assess analytical and bioinformatic approaches that enable cross-omics data integration, identifying bottlenecks and emerging opportunities. The review likely concludes with a prospective assessment of how these technologies may accelerate crop breeding and functional genomics research.
UK applicability
Although the review is international in scope, its findings are broadly applicable to UK crop science, where multi-omics approaches are increasingly embedded in precision breeding programmes relevant to wheat, barley and oilseed rape; UK researchers and plant breeders may draw on the methodological frameworks and future directions outlined to inform domestically funded genomics initiatives.
Key measures
Coverage of omics platforms and integration methodologies; crop traits addressed (e.g. yield, stress tolerance, nutrient use efficiency, quality); reported biological elements (genes, proteins, metabolites, regulatory networks)
Outcomes reported
The review surveys current progress in applying integrative multi-omics frameworks — encompassing genomics, transcriptomics, proteomics, metabolomics and epigenomics — to identify and characterise biological elements underpinning complex crop traits. It likely evaluates the strengths and limitations of each omics layer and the analytical approaches used to integrate them for crop improvement.
Topic tags
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