Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Biological control agents: mechanisms of action, selection, formulation and challenges in agriculture

Mirian Villavicencio-Vásquez; Fernando Espinoza; Lisbeth Espinoza-Lozano; Jonathan Coronel-León

Frontiers in Agronomy · 2025

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Summary

This review, published in Frontiers in Agronomy, provides a comprehensive synthesis of current knowledge on biological control agents used in agricultural pest and disease management, covering their principal mechanisms of action, criteria for strain or species selection, and formulation strategies. The authors, affiliated with institutions suggesting a Latin American perspective, likely draw on international literature to assess efficacy and stability challenges that impede BCA deployment at scale. The paper is expected to contribute a structured framework for understanding where BCAs fit within integrated pest management and what scientific and practical obstacles remain.

UK applicability

Although the paper is unlikely to focus specifically on UK conditions, its findings are broadly applicable to UK integrated pest management policy, particularly given increased pressure to reduce synthetic pesticide use under the UK's National Action Plan for the Sustainable Use of Pesticides and the expansion of approved biopesticide and biocontrol products regulated by the HSE.

Key measures

Mechanisms of action (antibiosis, competition, induced resistance, hyperparasitism); formulation types; efficacy indicators; barriers to commercialisation and field application

Outcomes reported

The paper likely reviews the modes of action of biological control agents (BCAs) — including bacteria, fungi, and other antagonists — and evaluates approaches to their selection, formulation, and deployment in crop production. It probably addresses the practical and regulatory challenges limiting wider BCA adoption in agriculture.

Theme
Farming systems, soils & land use
Subject
Crop protection & biological control
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Arable and horticultural systems (general)
DOI
10.3389/fagro.2025.1578915
Catalogue ID
NRmo3f02hq-01i

Topic tags

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