Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Chitosan-based formulations for therapeutic applications. A recent overview.

Gonciarz W, Balcerczak E, Brzeziński M, Jeleń A, Pietrzyk-Brzezińska AJ, Narayanan VHB, Chmiela M.

J Biomed Sci · 2025

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Summary

This 2025 narrative review, published in the Journal of Biomedical Science, provides an overview of recent advances in chitosan-based formulations for therapeutic use. Chitosan, a biopolymer derived from chitin, is examined in the context of its pharmacological versatility, including roles in targeted drug delivery, wound management, and antimicrobial applications. The review synthesises emerging evidence on formulation strategies and likely addresses bioavailability, safety profiles, and clinical potential, though specific findings should be verified against the full text.

UK applicability

Chitosan-based therapeutics are an active area of pharmaceutical and biomedical research globally, including within UK academic and clinical settings; findings from this international review would be broadly applicable to UK researchers and clinicians exploring biopolymer-based drug delivery or wound care innovations.

Key measures

Therapeutic efficacy indicators; drug delivery performance; antimicrobial and anti-inflammatory properties; biocompatibility and biodegradability assessments

Outcomes reported

The review surveys the therapeutic applications of chitosan-based formulations, likely covering drug delivery, wound healing, antimicrobial activity, and other biomedical uses reported across recent literature.

Theme
Nutrition & health
Subject
Biomedical materials & therapeutic delivery
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.1186/s12929-025-01161-7
Catalogue ID
NRmo3f02hq-024

Topic tags

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