Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Chronic Endometritis and Antimicrobial Resistance: Towards a Multidrug-Resistant Endometritis? An Expert Opinion.

Di Gennaro F, Guido G, Frallonardo L, Pennazzi L, Bevilacqua M, Locantore P, Vitagliano A, Saracino A, Cicinelli E.

Microorganisms · 2025

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Summary

This expert opinion paper addresses the emerging concern of antimicrobial resistance in chronic endometritis, a gynaecological condition increasingly implicated in reproductive failure and infertility. Drawing on available clinical and microbiological evidence, the authors assess whether resistance trends in causative pathogens may be giving rise to a multidrug-resistant form of the condition. The paper contributes to clinical guidance by highlighting the need for targeted antimicrobial stewardship strategies in the management of chronic endometritis.

UK applicability

Whilst the study does not appear to be UK-specific, the findings are broadly applicable to UK gynaecological and reproductive medicine practice, particularly given NHS commitments to antimicrobial stewardship and the UK National Action Plan on antimicrobial resistance. Clinicians managing chronic endometritis in the UK may find the resistance profiling and treatment considerations directly relevant.

Key measures

Antimicrobial resistance profiles of endometrial pathogens; prevalence of multidrug-resistant organisms; treatment response rates; microbiological culture and sensitivity data

Outcomes reported

The paper examines the prevalence and clinical implications of antimicrobial resistance in chronic endometritis, exploring whether current pathogen profiles and treatment failures are trending towards a multidrug-resistant phenotype. It likely reviews available evidence on causative organisms, resistance patterns, and therapeutic options.

Theme
Nutrition & health
Subject
Infectious disease & antimicrobial resistance
Study type
Commentary
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.3390/microorganisms13010197
Catalogue ID
NRmo3f02hq-061

Topic tags

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