Summary
This review, published in Frontiers in Veterinary Science (2025), examines the landscape of antibiotic alternatives for sustainable livestock production in the context of growing global antimicrobial resistance (AMR). Drawing on the One Health framework — which recognises the interdependence of human, animal, and environmental health — the authors likely assess the current evidence base for interventions including probiotics, prebiotics, phytogenic feed additives, bacteriophages, and vaccination strategies. The paper is likely intended to guide researchers, veterinarians, and policymakers in identifying practical and evidence-supported pathways to reduce antibiotic dependency in animal agriculture.
UK applicability
Highly applicable to UK conditions, where AMR is a national priority under the UK AMR National Action Plan and livestock antibiotic use is regulated and monitored by RUMA and the Veterinary Medicines Directorate; the review's international scope means specific intervention evidence would need contextualising to UK-approved products and regulatory frameworks.
Key measures
Antimicrobial resistance prevalence; efficacy of alternative interventions (e.g. probiotics, phytogenics, bacteriophages); animal health and production outcomes; One Health risk indicators
Outcomes reported
The paper likely reviews and evaluates a range of alternatives to antibiotics — such as probiotics, prebiotics, phytogenics, bacteriophages, and immunomodulators — assessing their efficacy, feasibility, and role in reducing antimicrobial resistance across livestock systems. It considers these alternatives through the One Health lens, addressing the interconnections between animal health, human health, and environmental sustainability.
Topic tags
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