Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Comprehensive Risk Assessment of Metals and Minerals in Seafood Using Bioaccessibility Correction

Ștefania Adelina Milea; Ira-Adeline Simionov; Nina Nicoleta Condurache; Cătalina Iticescu; Mihaela Timofti; L. Georgescu; Caterina Faggio

Journal of Xenobiotics · 2025

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Summary

This study applies bioaccessibility correction to metal and mineral data from seafood samples to produce more physiologically realistic dietary risk assessments than those based on total elemental concentrations alone. By accounting for the fraction of contaminants actually available for intestinal absorption, the authors likely demonstrate that conventional risk estimates may overstate or, in some cases, understate true human exposure. The work contributes methodological rigour to food safety surveillance and is relevant to regulatory frameworks governing seafood contaminant limits.

UK applicability

Although the study appears to be conducted in a Romanian or broader European context, its methodological approach to bioaccessibility-corrected risk assessment is directly relevant to UK food safety practice, particularly given the Food Standards Agency's ongoing work on dietary exposure to heavy metals through seafood consumption.

Key measures

Total metal concentrations (mg/kg wet weight); bioaccessible fractions (%); estimated daily intake (EDI); hazard quotient (HQ); hazard index (HI); carcinogenic risk (CR)

Outcomes reported

The study assessed human health risks associated with metal and mineral intake from seafood consumption, applying bioaccessibility correction factors to refine exposure estimates beyond total metal concentrations. It likely reported hazard quotients and/or carcinogenic risk indices for elements such as arsenic, cadmium, lead, mercury, and essential minerals.

Theme
Nutrition & health
Subject
Food safety & contaminants
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
Romania
System type
Food supply chain
DOI
10.3390/jox15030092
Catalogue ID
NRmo3f02hq-09l

Topic tags

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