Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

How to increase dietary polyphenol bioavailability: Understanding the roles of modulating factors, lifestyle and gut microbiota

Courage Sedem Dzah

Food and Humanity · 2025

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Summary

This narrative review examines the multifactorial determinants of polyphenol bioavailability, with attention to the interplay between food matrix properties, processing and preparation methods, individual lifestyle factors, and gut microbiota activity. The paper likely synthesises current evidence to identify practical strategies for enhancing the systemic availability of plant-derived polyphenols from the diet. It contributes to the growing body of literature connecting dietary quality, gut ecology, and the functional health potential of phytonutrients.

UK applicability

The findings are broadly applicable to UK dietary contexts, given that polyphenol-rich foods such as tea, berries, wholegrains, and vegetables are widely consumed in the UK; the review's insights may inform UK public health guidance on diet quality and gut microbiome support.

Key measures

Polyphenol bioavailability indicators (e.g. plasma concentration, urinary excretion); gut microbiota composition and metabolite production; dietary intake patterns; food processing effects on polyphenol bioaccessibility

Outcomes reported

The paper reviews the key factors that modulate the bioavailability of dietary polyphenols, including food matrix effects, processing methods, lifestyle variables, and gut microbiota composition. It likely synthesises evidence on how these factors interact to determine the extent to which polyphenols are absorbed and metabolised in the human body.

Theme
Nutrition & health
Subject
Phytonutrients & bioavailability
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.1016/j.foohum.2025.100602
Catalogue ID
NRmo3f02hq-0aw

Topic tags

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