Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Plant bioactive compounds: extraction, biological activities, immunological, nutritional aspects, food application, and human health benefits—A comprehensive review

Mohamed T. El‐Saadony; Ahmed M. Saad; Dina Mostafa Mohammed; Samar Sami Alkafaas; Taia A. Abd El–Mageed; Mohamed Abdelsabour Fahmy; Ahmed Ezzat Ahmed; Uthman Balgith Algopishi; Abdelghafar M. Abu-Elsaoud; Walid F. A. Mosa; Synan F. AbuQamar; Khaled A. El‐Tarabily

Frontiers in Nutrition · 2025

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Summary

This comprehensive narrative review synthesises peer-reviewed evidence on the extraction, characterisation, and biological activities of plant-derived bioactive compounds, including polyphenols, flavonoids, alkaloids, and related phytochemicals. It evaluates their immunological and nutritional significance, assesses current and emerging food application strategies, and consolidates findings on their role in supporting human health. The paper provides a broad reference framework for researchers and practitioners working at the intersection of plant science, food technology, and nutritional health.

UK applicability

Whilst the review is global in scope and not specific to UK agricultural or dietary conditions, its findings on bioactive compound extraction and health benefits are broadly applicable to UK food formulation, functional food development, and public health nutrition policy. UK researchers and food technologists may draw on this review to inform evidence-based product development and dietary guidance.

Key measures

Biological activity profiles (antioxidant, antimicrobial, anti-inflammatory); extraction method efficacy; immunomodulatory and nutritional parameters; food application outcomes; human health benefit indicators

Outcomes reported

The review examines extraction techniques, biological activities (including antioxidant, antimicrobial, and anti-inflammatory properties), and nutritional and immunological effects of plant bioactive compounds, alongside their applications in food systems and documented human health benefits.

Theme
Nutrition & health
Subject
Phytochemicals & functional nutrition
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
Global
System type
Food supply chain
DOI
10.3389/fnut.2025.1659743
Catalogue ID
NRmo3f02hq-0az

Topic tags

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