Summary
This systematic review synthesises published evidence on the application of plant-based diets in the management of chronic kidney disease (CKD). The paper evaluates the potential renoprotective mechanisms of plant-based eating patterns, including reduced dietary acid load, lower phosphate bioavailability, and modulation of the gut microbiome. The review provides a narrative account of clinical evidence supporting plant-based diets as a complementary intervention in CKD, whilst acknowledging gaps in mechanistic understanding and the absence of unified clinical guidance.
UK applicability
Whilst this review is international in scope and not UK-specific, its findings are broadly applicable to UK clinical practice and align with growing NHS and dietetic interest in plant-forward dietary approaches for CKD management; UK renal dietitians may find the synthesis of mechanisms and clinical outcomes useful in informing patient dietary advice.
Key measures
Kidney function markers (eGFR, serum creatinine); proteinuria; blood pressure; serum phosphate; serum potassium; metabolic acidosis indicators; cardiovascular risk markers
Outcomes reported
The study examined the effects of plant-based dietary patterns on kidney function and disease progression in CKD patients, reporting on outcomes including renal biomarkers, acid-base balance, phosphate and potassium management, and cardiovascular risk reduction.
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