Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

The Influence of an AI-Driven Personalized Nutrition Program on the Human Gut Microbiome and Its Health Implications

Konstantinos Rouskas; Mary Guela; Marianna Pantoura; Ioannis Pagkalos; Maria Hassapidou; Elena Lalama; Andreas Pfeiffer; Elise Decorte; Véronique Cornelissen; Saskia Wilson-Barnes; Kathryn Hart; Eugenio Mantovani; Sofia B. Dias; Leontios J. Hadjileontiadis; Lazaros Gymnopoulos; Kosmas Dimitropoulos; Anagnostis Argiriou

Nutrients · 2025

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Summary

This study investigated the effect of a six-week AI-based personalised nutrition programme on the gut microbiome of 29 healthy adults, using 16S rRNA sequencing alongside anthropometric and biochemical assessments. The research contributes to a growing body of evidence on the feasibility and efficacy of digital nutrition tools in modulating gut microbiota, with implications for dietary guidance and preventive health. As part of what appears to be a European collaborative project, the findings are likely to be relevant to the design of scalable, technology-assisted dietary interventions.

UK applicability

UK applicability is moderate; while the study was conducted across European sites and likely includes UK-based participants given the presence of UK-affiliated authors (Saskia Wilson-Barnes, Kathryn Hart from the University of Surrey), the findings on AI-assisted nutrition and gut microbiome responses are broadly relevant to UK public health and digital health policy contexts.

Key measures

Gut microbiome diversity and composition (16S rRNA amplicon sequencing); anthropometric measures (e.g. BMI, body weight); biochemical blood markers; dietary intake (food frequency questionnaire)

Outcomes reported

The study measured changes in gut microbiome composition (via 16S rRNA amplicon sequencing), anthropometric parameters, and biochemical blood markers in healthy adults following a six-week AI-based personalised nutrition intervention. It assessed whether an AI-driven mobile application could meaningfully shift gut microbial diversity and abundance in a health-promoting direction.

Theme
Nutrition & health
Subject
Gut microbiome & personalised nutrition
Study type
Research
Study design
Controlled intervention study
Source type
Peer-reviewed study
Status
Published
Geography
Europe
System type
Human clinical
DOI
10.3390/nu17071260
Catalogue ID
NRmo3f02hq-0dg

Topic tags

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