Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewed

Impact of Substituting Meats with Plant-Based Analogues on Health-Related Markers: A Systematic Review of Human Intervention Studies.

Del Bo' C, Chehade L, Tucci M, Canclini F, Riso P, Martini D.

Nutrients · 2024

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Summary

This systematic review synthesised evidence from human intervention studies comparing the health effects of substituting conventional meat with plant-based meat analogues. The authors examined changes in health-related biomarkers across included trials to assess whether plant-based alternatives confer metabolic or cardiovascular benefits relative to conventional meat consumption. The review contributes to understanding whether reformulated meat analogues represent a nutritionally equivalent substitution from a human health perspective.

UK applicability

Findings are applicable to UK dietary recommendations and public health policy, particularly given the Eatwell Guide's encouragement of plant-based protein sources and growing commercial availability of meat alternatives in UK retail. The evidence base would inform UK health professionals and consumers evaluating the health case for meat alternative adoption.

Key measures

Health-related biomarkers including lipid profiles, blood pressure, inflammatory markers, glucose metabolism, and other cardiovascular and metabolic endpoints

Outcomes reported

The study systematically reviewed human intervention trials examining changes in health-related biomarkers (cardiovascular, metabolic, inflammatory markers) when conventional meat products were replaced with plant-based meat analogues. Outcomes likely included lipid profiles, blood pressure, glucose metabolism, and inflammatory markers.

Theme
Nutrition & health
Subject
Plant-based protein alternatives and cardiometabolic health outcomes
Study type
Systematic Review
Study design
Systematic review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.3390/nu16152498
Catalogue ID
NRmo9zxr64-07p

Topic tags

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