Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Tumor biomarkers for diagnosis, prognosis and targeted therapy.

Zhou Y, Tao L, Qiu J, Xu J, Yang X, Zhang Y, Tian X, Guan X, Cen X, Zhao Y.

Signal Transduct Target Ther · 2024

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Summary

This review article examines the current landscape of tumour biomarkers and their utility in clinical oncology. The authors likely synthesise evidence on molecular, genetic and protein-based biomarkers used to diagnose cancers, predict patient outcomes and guide precision medicine approaches. The work appears positioned as a comprehensive overview of biomarker discovery, validation and implementation in cancer care.

UK applicability

Findings are applicable to UK cancer diagnostics and NHS treatment pathways, where biomarker-driven precision oncology is increasingly integrated into standard care. However, implementation depends on diagnostic infrastructure, NHS capacity and health economic decisions.

Key measures

Biomarker sensitivity, specificity, prognostic value, predictive utility for treatment selection

Outcomes reported

The study reviewed the role of tumour biomarkers in cancer diagnosis, prognostication and selection of targeted therapeutic interventions. It synthesised evidence on biomarker classes and their clinical applications across cancer types.

Theme
Nutrition & health
Subject
Cancer diagnostics and precision medicine
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
System type
Human clinical
DOI
10.1038/s41392-024-01823-2
Catalogue ID
NRmo9zxr64-09h

Topic tags

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