Summary
This narrative review synthesises contemporary evidence on pathways to cervical cancer elimination in high-income countries, with emphasis on human papillomavirus vaccination and screening programme effectiveness. The authors identify multifactorial barriers—clinical, organisational, and policy-level—that currently constrain progress towards elimination. The work suggests that whilst substantial progress has been achieved in resource-rich settings, sustained, coordinated investment across prevention, detection, and treatment remains necessary for elimination targets to be realised.
UK applicability
The findings are directly applicable to United Kingdom cervical cancer policy and practice, as the UK operates within a high-income healthcare context with established HPV vaccination and cervical screening programmes. The identified organisational and policy challenges are likely relevant to NHS implementation and devolved health policy in England, Scotland, Wales, and Northern Ireland.
Key measures
Cervical cancer incidence and mortality trends; HPV vaccination coverage rates; screening programme performance; policy implementation barriers; clinical and organisational capacity metrics (as inferred from scope)
Outcomes reported
The review synthesised evidence on cervical cancer elimination strategies, examining the effectiveness of human papillomavirus vaccination and screening programmes alongside identified barriers to progress. It assessed clinical, organisational, and policy-level challenges impeding elimination in high-income country contexts.
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