Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Minimally Invasive Surgery for Cervical Cancer in Light of the LACC Trial: What Have We Learned?

Omar Touhami, Marie Plante

Current Oncology · 2022

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Summary

Cervical cancer is the most common gynecologic malignancy and the fourth most common cancer in women worldwide. Over the last two decades, minimally invasive surgery (MIS) emerged as the mainstay in the surgical management of cervical cancer, bringing advantages such as lower operative morbidity and shorter hospital stay compared to open surgery while maintaining comparable oncologic outcomes in numerous retrospective studies. However, in 2018, a prospective phase III randomized controlled trial, "Laparoscopic Approach to Carcinoma of the Cervix (LACC)", unexpectedly reported that MIS was associated with a statistically significant poorer overall survival and disease-free survival compared to open surgery in patients with early-stage cervical cancer. Various hypotheses have been raised by

Source type
Peer-reviewed study
DOI
10.3390/curroncol29020093
Catalogue ID
SNmoht1vhk-txputg
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