Pulse Brain · Growing Health Evidence Index
Peer-reviewed

The Potential of NGTs to Overcome Constraints in Plant Breeding and Their Regulatory Implications

Franziska Koller

International Journal of Molecular Sciences · 2025

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Summary

Conventional plant breeding relies on the occurrence of chromosomal crossover and spontaneous or non-targeted mutations in the genome induced by physical or chemical stressors. However, constraints exist concerning the number and variation of genotypes that can be achieved in this way, as the occurrence and combination of mutations are not equally distributed across the genome. The underlying mechanisms and causes of reproductive constraints can be considered the result of evolution to maintain the genomic stability of a species while at the same time allowing necessary adaptations. A continuous horizon scan was carried out to identify plants derived from new genomic techniques (NGTs), which show that CRISPR/Cas is able to circumvent at least some of these mechanisms and constraints. The r

Source type
Peer-reviewed study
DOI
10.3390/ijms262311391
Catalogue ID
SNmoi1qbgc-w6f8sz
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