Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Mechanisms and Future of Non-Small Cell Lung Cancer Metastasis

Tianhao Zhu, Xunxia Bao, Mingyu Chen, Rui Lin, Jianan Zhuyan, Timing Zhen, Kaichen Xing, Wei Zhou, Sibo Zhu

Frontiers in Oncology · 2020

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Summary

Lung cancer, renowned for its fast progression and metastatic potency, is rising to become a leading cause of death globally. It has been long observed that lung cancer is particularly ept in spawning distant metastasis at its early stages, and it can readily colonize virtually any human organ. In recent years, cancer research has shed light on why lung cancer is endowed with its exceptional ability to metastasize. In this review, we will take a comprehensive look at the current research on lung cancer metastasis, including molecular pathways, anatomical features and genetic traits that make lung cancer intrinsically metastatic, as we go from lung cancer's general metastatic potential to the particular metastasis mechanisms in multiple organs. We highly concerned about the advanced discove

Source type
Peer-reviewed study
DOI
10.3389/fonc.2020.585284
Catalogue ID
SNmoi53k0y-sgdum1
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