Pulse Brain · Growing Health Evidence Index
Peer-reviewed

PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway

Jing Luo, Yu Yao, Saiguang Ji, Qi Sun, Yang Xu, Kaichao Liu, Qiang Diao, Yong Qiang, Yi Shen

Cancer Cell International · 2019

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Summary

Up-regulation of PITX2 acts as an oncogene in LUAD by activating Wnt/β-catenin signaling pathway, suggesting that PITX2 may serve as a novel diagnostic and prognostic biomarker in LUAD.

Source type
Peer-reviewed study
DOI
10.1186/s12935-019-0800-7
Catalogue ID
SNmoi53mbt-5b9n1p
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