Pulse Brain · Growing Health Evidence Index
Peer-reviewed

MiR-532-5p suppresses renal cancer cell proliferation by disrupting the ETS1-mediated positive feedback loop with the KRAS-NAP1L1/P-ERK axis

Wei Zhai, Junjie Ma, Rujian Zhu, Xu Chen, Jin Zhang, Yonghui Chen, Zhiguo Chen, Dongkui Gong, Jiayi Zheng, Chen Chen, Saiyang Li, Butang Li, Yong Huang, Wei Xue, Junhua Zheng

British Journal of Cancer · 2018

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Summary

Our work presents a road map for the prediction and validation of a miR-532-5p/KRAS-NAP1L1/P-ERK/ETS1 axis feedback loop regulating cell proliferation, which could potentially provide better therapeutic avenues for treating RCC.

Source type
Peer-reviewed study
DOI
10.1038/s41416-018-0196-5
Catalogue ID
SNmoi8o7l4-m2silu
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