Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Development of a real-time boron imaging method for BNCT using CdTe-DSD at the JRR-3

I. Chiu, Takahito Osawa, Takehiro Sumita, Mizuha Ikeda, Kazuhiko Ninomiya, Shin’ichiro Takeda, Takahiro Minami, Tadayuki Takahashi, Shin Watanabe

Applied Radiation and Isotopes · 2025

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Summary

Boron neutron capture therapy (BNCT) is a neutron-based cancer treatment requiring a real-time <sup>10</sup>B dose monitor to optimize effectiveness. We report using of the cadmium telluride double-sided strip detector (CdTe-DSD), distinguished by its high-energy resolution in full width at half maximum (FWHM) of 7.3 keV at 511 keV and a spatial resolution of 250μm for accurate boron imaging. Employing the CdTe-DSD with a pinhole collimator, our experiment at Japan Research Reactor No. 3 (JRR-3) evaluated the <sup>10</sup>B distribution in a solid sample containing a <sup>10</sup>B concentration of 0.3 mg during neutron exposure. Although measuring the <sup>10</sup>B signal is significantly affected by the background from the γ-rays of <sup>113</sup>Cd, we successfully obtained a circular

Source type
Peer-reviewed study
DOI
10.1016/j.apradiso.2025.111845
Catalogue ID
SNmoic23jt-8jo50j
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