Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Simultaneous in vivo imaging with PET and SPECT tracers using a Compton-PET hybrid camera

Mizuki Uenomachi, M. Takahashi, Kenji Shimazoe, Hiroyuki Takahashi, Kei Kamada, Tadashi Orita, Kenichiro Ogane, Atsushi B. Tsuji

Scientific Reports · 2021

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Summary

Positron-emission tomography (PET) and single-photon-emission computed tomography (SPECT) are well-established nuclear-medicine imaging methods used in modern medical diagnoses. Combining PET with <sup>18</sup>F-fluorodeoxyglucose (FDG) and SPECT with an <sup>111</sup>In-labelled ligand provides clinicians with information about the aggressiveness and specific types of tumors. However, it is difficult to integrate a SPECT system with a PET system because SPECT requires a collimator. Herein, we describe a novel method that provides simultaneous imaging with PET and SPECT nuclides by combining PET imaging and Compton imaging. The latter is an imaging method that utilizes Compton scattering to visualize gamma rays over a wide range of energies without requiring a collimator. Using Compton ima

Source type
Peer-reviewed study
DOI
10.1038/s41598-021-97302-7
Catalogue ID
SNmoic288b-iq3w5y
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