Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Simultaneous multi-nuclide imaging via double-photon coincidence method with parallel hole collimators

Mizuki Uenomachi, Kenji Shimazoe, Kenichiro Ogane, Hiroyuki Takahashi

Scientific Reports · 2021

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Summary

Multi-tracer imaging can provide useful information in the definitive diagnosis and research of medical, biological, and pharmaceutical sciences. Single-photon emission computed tomography (SPECT) is one of the nuclear medicine imaging modalities widely used for diagnosis or medical research and has a multi-tracer imaging capability. One of the drawbacks of multi-tracer imaging is crosstalk from other gamma rays, which affects the reconstructed image. Scattering correction methods, such as the dual- and triple-energy window methods, are used for conventional SPECT imaging to reduce the background caused by the crosstalk. This study proposes another crosstalk reduction method. Some nuclides emit two or more gamma rays through intermediate levels. Thus, detecting these gamma rays with the co

Source type
Peer-reviewed study
DOI
10.1038/s41598-021-92583-4
Catalogue ID
SNmoic288b-lyk4kn
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