Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Imaging and sensing of pH and chemical state with nuclear-spin-correlated cascade gamma rays via radioactive tracer

Kenji Shimazoe, Mizuki Uenomachi, Hiroyuki Takahashi

Communications Physics · 2022

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Summary

Abstract Single-photon-emission computed tomography (SPECT) and positron-emission tomography (PET) are highly sensitive molecular detection and imaging techniques that generally measure accumulation of radio-labeled molecules by detecting gamma rays. Quantum sensing of local molecular environment via spin, such as nitrogen vacancy (NV) centers, has also been reported. Here, we describe quantum sensing and imaging using nuclear-spin time-space correlated cascade gamma-rays via a radioactive tracer. Indium-111 ( 111 In) is widely used in SPECT to detect accumulation using a single gamma-ray photon. The time-space distribution of two successive cascade gamma-rays emitted from an 111 In atom carries significant information on the chemical and physical state surrounding molecules with double ph

Source type
Peer-reviewed study
DOI
10.1038/s42005-022-00801-w
Catalogue ID
SNmoic288b-xckisj
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