Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Use of a Si/CdTe Compton Camera for In vivo Real-Time Monitoring of Annihilation Gamma Rays Generated by Carbon Ion Beam Irradiation

Shintaro Shiba, Raj Kumar Parajuli, Makoto Sakai, Takahiro Oike, Tatsuya Ohno, Takashi Nakano

Frontiers in Oncology · 2020

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Summary

The application of annihilation gamma-ray monitoring to the adaptive therapy of carbon ion radiotherapy (C-ion RT) requires identification of the peak intensity position and confirmation of activated elements with annihilation gamma-rays generated at the C-ion-irradiated site from those transported to unirradiated sites. Real-time monitoring of C-ion-induced annihilation gamma-rays was implemented using a Compton camera in a mouse model. An adult C57BL/6 mouse was anesthetized, and C-ion beams were directed into the abdomen at 1 × 10<sup>9</sup> particles/s for 20 s. The 511 keV annihilation gamma-rays, generated by the interaction between the irradiated C-ion beam and the target mouse, were detected using a silicon/cadmium telluride (Si/CdTe) Compton camera for 20 min immediately after ir

Source type
Peer-reviewed study
DOI
10.3389/fonc.2020.00635
Catalogue ID
SNmoic28zx-ueljur
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