Pulse Brain · Growing Health Evidence Index
Peer-reviewed

MASLD: a systemic metabolic disorder with cardiovascular and malignant complications

Giovanni Targher, Christopher D. Byrne, Herbert Tilg

Gut · 2024

Read source ↗ All evidence

Summary

Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a multisystem disease where systemic insulin resistance and related metabolic dysfunction play a pathogenic role in the development of NAFLD and its most relevant liver-related morbidities (cirrhosis, liver failure and hepatocellular carcinoma) and extrahepatic complications, such as cardiovascular disease (CVD), type 2 diabetes mellitus, chronic kidney disease, and certain types of extrahepatic cancers. In 2023, three large multinational liver associations proposed that metabolic dysfunction-associated steatotic liver disease (MASLD) should replace the term NAFLD; the name chosen to replace non-a

Source type
Peer-reviewed study
DOI
10.1136/gutjnl-2023-330595
Catalogue ID
SNmoixnufz-4e8i1a
Pulse AI · ask about this record

Dig deeper with Pulse AI.

Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.