Pulse Brain · Growing Health Evidence Index
Peer-reviewed

GLP-1 Receptor Agonists and Related Mental Health Issues; Insights from a Range of Social Media Platforms Using a Mixed-Methods Approach

Davide Arillotta, Giuseppe Floresta, Amira Guirguis, John Corkery, Valeria Catalani, Giovanni Martinotti, Stefano L. Sensi, Fabrizio Schifano

Brain Sciences · 2023

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Summary

The emergence of glucagon-like peptide-1 receptor agonists (GLP-1 RAs; semaglutide and others) now promises effective, non-invasive treatment of obesity for individuals with and without diabetes. Social media platforms’ users started promoting semaglutide/Ozempic as a weight-loss treatment, and the associated increase in demand has contributed to an ongoing worldwide shortage of the drug associated with levels of non-prescribed semaglutide intake. Furthermore, recent reports emphasized some GLP-1 RA-associated risks of triggering depression and suicidal thoughts. Consistent with the above, we aimed to assess the possible impact of GLP-1 RAs on mental health as being perceived and discussed in popular open platforms with the help of a mixed-methods approach. Reddit posts yielded 12,136 comm

Source type
Peer-reviewed study
DOI
10.3390/brainsci13111503
Catalogue ID
SNmoixnxa3-5gavrm
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