Pulse Brain · Growing Health Evidence Index
Peer-reviewed

The <i>MS4A</i> gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk

Yuetiva Deming, Fabia Filipello, Francesca Cignarella, Claudia Cantoni, Simon Hsu, Robert Mikesell, Zeran Li, Jorge L. Del‐Aguila, Umber Dube, Fabiana Farias, Joseph Bradley, John Budde, Laura Ibáñez, María Victoria Fernández, Kaj Blennow, Henrik Zetterberg, Amanda Heslegrave, Per Johansson, Johan Svensson, Bengt Nellgård, Alberto Lleó, Daniel Alcolea, Jordi Clarimón, Lorena Rami, José Luís Molinuevo, Marc Suárez‐Calvet, Estrella Morenas‐Rodríguez, Gernot Kleinberger, Michael Ewers, Oscar Harari, Christian Haass, Tom J. Brett, Bruno A. Benítez, Celeste M. Karch, Laura Piccio, Carlos Cruchaga

Science Translational Medicine · 2019

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Summary

risk-variant carriers but also in those with sporadic disease.

Source type
Peer-reviewed study
DOI
10.1126/scitranslmed.aau2291
Catalogue ID
SNmoj1xzzm-rlidxe
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