Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Maternal gut microbiota in the health of mothers and offspring: from the perspective of immunology

Xiaowen Lu, Zhan Shi, Lingling Jiang, Songying Zhang

Frontiers in Immunology · 2024

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Summary

Due to the physiological alteration during pregnancy, maternal gut microbiota changes following the metabolic processes. Recent studies have revealed that maternal gut microbiota is closely associated with the immune microenvironment in utero during pregnancy and plays a vital role in specific pregnancy complications, including preeclampsia, gestational diabetes, preterm birth and recurrent miscarriages. Some other evidence has also shown that aberrant maternal gut microbiota increases the risk of various diseases in the offspring, such as allergic and neurodevelopmental disorders, through the immune alignment between mother and fetus and the possible intrauterine microbiota. Probiotics and the high-fiber diet are effective inventions to prevent mothers and fetuses from diseases. In this r

Source type
Peer-reviewed study
DOI
10.3389/fimmu.2024.1362784
Catalogue ID
SNmoj1y1io-fye8zn
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