Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Association of systemic immune inflammatory index with all-cause and cause-specific mortality in hypertensive individuals: Results from NHANES

Yang Cao, Pengxiao Li, Yan Zhang, Miaohan Qiu, Jing Li, Sicong Ma, Yudong Yan, Yi Li, Yaling Han

Frontiers in Immunology · 2023

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Summary

Background: The relationship between the systemic immune inflammatory index (SII) and the prognosis of hypertensive patients is unclear. This study aims to explore the association of SII with all-cause and cause-specific mortality in patients with hypertension. Methods: This study included 8524 adults with hypertension from the National Health and Nutritional Examination Surveys (NHANES) 2011-2018, and followed for survival through December 31, 2019. Cox proportional hazards models were used to investigate the associations between SII and mortality from all causes, cardiovascular disease (CVD), and cancer. Restricted cubic spline, piecewise linear regression, subgroup and sensitivity analyses were also used. Results: During a median follow-up of 4.58 years, 872 all-cause deaths occurred. A

Subject
Dietary patterns & chronic disease
Source type
Peer-reviewed study
System type
Other
DOI
10.3389/fimmu.2023.1087345
Catalogue ID
SNmoj1ypb9-lb1y6f
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