Pulse Brain · Growing Health Evidence Index
Peer-reviewed

The Implications of Aging on Vascular Health

Bulbul Ahmed, Ahmed A. Rahman, Sujin Lee, Rajeev Malhotra

International Journal of Molecular Sciences · 2024

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Summary

Vascular aging encompasses structural and functional changes in the vasculature, significantly contributing to cardiovascular diseases, which are the leading cause of death globally. The incidence and prevalence of these diseases increase with age, with most morbidity and mortality attributed to myocardial infarction and stroke. Diagnosing and intervening in vascular aging while understanding the mechanisms behind age-induced vascular phenotypic and pathophysiological alterations offers the potential for delaying and preventing cardiovascular mortality in an aging population. This review delves into various aspects of vascular aging by examining age-related changes in arterial health at the cellular level, including endothelial dysfunction, cellular senescence, and vascular smooth muscle c

Source type
Peer-reviewed study
DOI
10.3390/ijms252011188
Catalogue ID
SNmoj7no8t-o7kt3y
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