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Peer-reviewed

Neurological Aspects of SARS-CoV-2 Infection: Mechanisms and Manifestations

Parménides Guadarrama-Ortíz, José Alberto Choreño-Parra, Claudia Marisol Sánchez-Martínez, Francisco Javier Pacheco-Sánchez, Alberto Iván Rodríguez-Nava, Gabriela García-Quintero

Frontiers in Neurology · 2020

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Summary

The human infection of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a public health emergency of international concern that has caused more than 16.8 million new cases and 662,000 deaths as of July 30, 2020. Although coronavirus disease 2019 (COVID-19), which is associated with this virus, mainly affects the lungs, recent evidence from clinical and pathological studies indicates that this pathogen has a broad infective ability to spread to extrapulmonary tissues, causing multiorgan failure in severely ill patients. In this regard, there is increasing preoccupation with the neuroinvasive potential of SARS-CoV-2 due to the observation of neurological manifestations in COVID-19 patients. This concern is also supported by the neurotropism previously documented in o

Source type
Peer-reviewed study
DOI
10.3389/fneur.2020.01039
Catalogue ID
SNmoj7nv2v-n0k4ae
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