Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Artificial intelligence in cancer target identification and drug discovery

Yujie You, Xin Lai, Yi Pan, Huiru Zheng, Julio Vera, Suran Liu, Senyi Deng, Le Zhang

Signal Transduction and Targeted Therapy · 2022

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Summary

Artificial intelligence is an advanced method to identify novel anticancer targets and discover novel drugs from biology networks because the networks can effectively preserve and quantify the interaction between components of cell systems underlying human diseases such as cancer. Here, we review and discuss how to employ artificial intelligence approaches to identify novel anticancer targets and discover drugs. First, we describe the scope of artificial intelligence biology analysis for novel anticancer target investigations. Second, we review and discuss the basic principles and theory of commonly used network-based and machine learning-based artificial intelligence algorithms. Finally, we showcase the applications of artificial intelligence approaches in cancer target identification and

Source type
Peer-reviewed study
DOI
10.1038/s41392-022-00994-0
Catalogue ID
SNmojad3ph-eakooy
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