Pulse Brain · Growing Health Evidence Index
Peer-reviewed

The comprehensive effects of high-sensitivity C-reactive protein and triglyceride glucose index on cardiometabolic multimorbidity

Bingen Wan, Silin Wang, Sheng Hu, Weiqing Han, Shengyu Qiu, Lingxiao Zhu, Liancheng Ruan, Yiping Wei, Jianjun Xu

Frontiers in Endocrinology · 2025

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Summary

Background: The triglyceride-glucose index (TyG index) is one of the surrogate markers of insulin resistance, and high-sensitivity C-reactive protein (hsCRP) reflects systemic inflammation. Existing studies suggest that insulin resistance or systemic inflammation may be indicative of cardiometabolic disease, but few of the existing studies have combined the TyG index and inflammation levels before assessing cardiometabolic multimorbidity. Our study data came from the China Health and Retirement Longitudinal Study (CHARLS). Participants in this data were followed for 9 years, and we used these data to conduct a long-term analysis to assess the combined effects of the TyG index and hsCRP on cardiometabolic multimorbidity in Chinese adults over 45 years of age. Purpose: To study the combined

Source type
Peer-reviewed study
DOI
10.3389/fendo.2025.1511319
Catalogue ID
SNmojad4a5-04rblh
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